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Optical pharmacokinetics to assess the permeability of angiogenic neovasculature

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Abstract

The method of Optical Pharmacokinetics is used for noninvasive measurement of drug concentrations in tissue. A rapid sequence of such measurements, following administration of a short bolus of appropriate optical contrast agent, can be used to assess the permeability of neovasculature, hence angiogenesis.

© 2002 Optical Society of America

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