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Three-dimensional optical images of the brains of newborn infants have been generated which reveal induced changes in the blood content and oxygenation. A 32-channel time-resolved imaging system has been employed to acquire data on a mechanically ventilated infant during alterations to the ventilator settings, and on other infants during passive motor stimulus. Measurements of the flight times of photons transmitted across the brain at wavelengths of 780 nm and 815 nm have been utilized to reconstruct images representing spatially localized differences in absorption, and the concentrations of oxy- and deoxy-hemoglobin.
© 2004 Optical Society of America
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