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Fluorescence Lifetime Imaging Microscopy (FLIM) Measures Oxygen Gradients in Microfluidic Bioreactors

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Abstract

A unique FLIM system was employed to quantitatively image extracellular oxygen distributions in perfused micro-bioreactors. We report effects of cell density on oxygen consumption and the first such measurement of oxygen gradients formed within micro-bioreactors

© 2006 Optical Society of America

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