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Conferences > BIOMED > 2010 > BMC > BMC6

Femtosecond Laser Ablation to Induce Occlusions in Single, Targeted Venules in Rat Brain

John Nguyen, Nozomi Nishimura, Costantino Iadecola, and Chris B. Schaffer

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Abstract

Femtosecond laser induced photodisruption is used to clot single venules in live, anesthetized rats. Two-photon excited fluorescence imaging shows significant decreases in blood flow speeds and increases in diameter in capillaries upstream from the clot.

© 2010 Optical Society of America

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