Accurate Study of FosPeg® Distribution in a Mouse Model Using Fluorescence Imaging Technique and Fluorescence White Monte Carlo Simulations

Haiyan Xie; Haichun Liu; Pontus Svenmarker; Johan Axelsson; Susanna Gräfe; Jesper Holm Lundeman; Haynes Cheng; Maria Kyriazi; Niels Bendsoe; Peter Andersen; Katarina Svanberg; Stefan Andersson-Engels

doi:10.1364/BIOMED.2010.BTuD6

Biomedical Optics and 3-D Imaging
OSA Technical Digest (CD) (Optica Publishing Group, 2010),
paper BTuD6
•https://doi.org/10.1364/BIOMED.2010.BTuD6

Accurate Study of FosPeg^® Distribution in a Mouse Model Using Fluorescence Imaging Technique and Fluorescence White Monte Carlo Simulations

Haiyan Xie, Haichun Liu, Pontus Svenmarker, Johan Axelsson, Susanna Gräfe, Jesper Holm Lundeman, Haynes Cheng, Maria Kyriazi, Niels Bendsoe, Peter Andersen, Katarina Svanberg, and Stefan Andersson-Engels

Biomedical Optics 2010

Miami, Florida United States
11–14 April 2010
ISBN: 978-1-55752-887-2

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H. Xie, H. Liu, P. Svenmarker, J. Axelsson, S. Gräfe, J. H. Lundeman, H. Cheng, M. Kyriazi, N. Bendsoe, P. Andersen, K. Svanberg, and S. Andersson-Engels, "Accurate Study of FosPeg® Distribution in a Mouse Model Using Fluorescence Imaging Technique and Fluorescence White Monte Carlo Simulations," in Biomedical Optics and 3-D Imaging, OSA Technical Digest (CD) (Optica Publishing Group, 2010), paper BTuD6.

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Abstract

Fluorescence imaging is used for quantitative in vivo assessment of drug concentration. Light attenuation in tissue is compensated for through Monte-Carlo simulations. The intrinsic fluorescence intensity, directly proportional to the drug concentration, could be obtained.

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