It is shown that an analytic expression of fluorescence ratio detection can provide a direct estimate of depth in multi-spectral sub-surface imaging. This is supported by preliminary fluorescence data acquired with a broad-beam multi-spectral system.
© 2010 OSA
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.4580) Medical optics and biotechnology : Optical diagnostics for medicine
(300.0300) Spectroscopy : Spectroscopy
(300.6280) Spectroscopy : Spectroscopy, fluorescence and luminescence
F. Leblond, Z. Ovanesyan, S. C. Davis, V. Krishnaswamy, P. A. Valdes, A. Kim, B. C. Wilson, A. Hartov, B. W. Pogue, K. D. Paulsen, and D. W. Roberts, "Towards Depth-Resolved Fluorescence-Guided Surgery Using Multi-Spectral Near-Infrared Light," in Biomedical Optics and 3-D Imaging, OSA Technical Digest (CD) (Optical Society of America, 2010), paper BTuD97.
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