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  • Conference on Lasers and Electro-Optics/Quantum Electronics and Laser Science Conference and Photonic Applications Systems Technologies
  • OSA Technical Digest (CD) (Optica Publishing Group, 2008),
  • paper CWM4

Three-dimensional Motion of a Nanoparticle on the Cell Membrane Observed by Non-interferometric Widefield Optical Profilometry

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Abstract

We directly observe three-dimensional motion of a gold nanoparticle on the membrane of a living cell by using non-interferometric widefield optical profilometry. We identify the occurrence of particle internalization and actin aggregation which indicates endocytosis.

© 2008 Optical Society of America

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