Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group

“Nerve Regeneration after Femtosecond Laser Nano-axotomy”

Open Access Open Access

Abstract

We demonstrate nanoscale surgery with femtosecond lasers in a tiny living organism. By just cutting few nano-scale nerve connections inside C. elegans, we succeeded to stop the whole animal from moving backwards. This delicate axotomy keeps the surrounding of the severed axons un-damaged so that the axons can regrow back and the worms recover and can move backwards again. These results demonstrate, for the first time, nerve regeneration in such a tiny organism. The ability to perform precise nano-surgery on such organisms provides tremendous research potential for rapid screening of drugs and discovery of new biomolecules affecting regeneration and development.

© 2005 Optical Society of America

PDF Article
More Like This
Nerve Regeneration in C. elegans after Femtosecond Laser Nano-Surgery

Mehmet Yanik, Hulusi Cinar, Hediye Cinar, Andrew Chisholm, Yishi Jin, and Adela Ben-Yakar
CPDA8 Conference on Lasers and Electro-Optics (CLEO:S&I) 2005

In vivo two-photon imaging of climbing fibers plasticity after laser axotomy

A. L. Allegra Mascaro, P. Cesare, L. Sacconi, G. Grasselli, G. Mandolesi, B. Maco, G. W. Knott, V. De Paola, P. Strata, and F.S. Pavone
880407 European Conference on Biomedical Optics (ECBO) 2013

High-throughput in vivo genetic and drug screening using femtosecond laser microsurgery and microfluidics

C. B. Rohde, F. Zeng, C. Gilleland, R. Gonzalez-Rubio, M. Angel, and M. F. Yanik
CFE1 Conference on Lasers and Electro-Optics (CLEO:S&I) 2008

Select as filters


Select Topics Cancel
© Copyright 2024 | Optica Publishing Group. All Rights Reserved