Quantitative Detection of Near Infrared-labeled Transferrin using FRET Fluorescence Lifetime Wide-Field Imaging in Breast Cancer Cells In Vitro and In Vivo

Ken Abe; Lingling Zhao; Xavier Intes; Margarida Barroso

doi:10.1364/QMI.2013.QTu3G.5

Imaging and Applied Optics
OSA Technical Digest (online) (Optica Publishing Group, 2013),
paper QTu3G.5
•https://doi.org/10.1364/QMI.2013.QTu3G.5

Quantitative Detection of Near Infrared-labeled Transferrin using FRET Fluorescence Lifetime Wide-Field Imaging in Breast Cancer Cells In Vitro and In Vivo

Ken Abe, Lingling Zhao, Xavier Intes, and Margarida Barroso

Quantitative Medical Imaging 2013

Arlington, Virginia United States
23–27 June 2013
ISBN: 978-1-55752-975-6

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Diagnostic Optical Technologies (QTu3G)

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K. Abe, L. Zhao, X. Intes, and M. Barroso, "Quantitative Detection of Near Infrared-labeled Transferrin using FRET Fluorescence Lifetime Wide-Field Imaging in Breast Cancer Cells In Vitro and In Vivo," in Imaging and Applied Optics, OSA Technical Digest (online) (Optica Publishing Group, 2013), paper QTu3G.5.

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Abstract

A novel near infrared FRET fluorescence lifetime imaging technique with wide-field illumination strategies was developed to validate and characterize cellular uptake of transferrin in both cancer cells and normal cells in vitro and in vivo.

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