Abstract

We present compensating methods that address inherent errors in quantitative phase reporting for low-coherence interferometric techniques. A brief theoretical treatment of the problem and experimental validation using spectral domain phase microscopy demonstrate mitigation of the degrading effects of phase leakage on accurate measurement of optical path length in the vicinity of closely spaced reflectors. This result has direct implications for phase-sensitive interferometry techniques, such as Doppler imaging, as well as amplitude-based quantitative reporting. Corrected phase retrieval is demonstrated for conversion of interferometric phase to optical path length in cell surface deflections of beating cardiomyocytes.

© 2007 Optical Society of America

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History
Original Manuscript: August 29, 2006
Revised Manuscript: November 11, 2006
Manuscript Accepted: November 16, 2006
Published: January 26, 2007

References

Author Affiliations

Audrey K. Ellerbee, Joseph A. Izatt

Duke University

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