Three-dimensional fluorescence optical tomography in small-animal imaging using simultaneous positron-emission-tomography priors
Optics Letters, Vol. 34, Issue 19, pp. 2933-2935 doi:10.1364/OL.34.002933
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- OCIS Codes:
- (170.3880) Medical optics and biotechnology : Medical and biological imaging
- (170.3890) Medical optics and biotechnology : Medical optics instrumentation
- (170.6960) Medical optics and biotechnology : Tomography
Medical Optics and Biotechnology
Citation
Changqing Li, Guobao Wang, Jinyi Qi, and Simon R. Cherry, "Three-dimensional fluorescence optical tomography in small-animal imaging using simultaneous positron-emission-tomography priors," Opt. Lett. 34, 2933-2935 (2009)
http://www.opticsinfobase.org/abstract.cfm?URI=ol-34-19-2933
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- Vol. 4, Iss. 12 Virtual Journal for Biomedical Optics
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We propose three-dimensional fluorescence optical tomography imaging for small animals guided by simultaneous priors from positron emission tomography (PET). Using a sparsity regularization, the target prior from PET images was incorporated into the reconstruction algorithm for optical imaging. The method and algorithms are validated with numerical simulations and a phantom experiment performed on a combined optical-PET scanner based on a conical mirror geometry.
© 2009 Optical Society of America
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History
Original Manuscript: April 14, 2009
Manuscript Accepted: August 24, 2009
Revised Manuscript: August 6, 2009
Published: September 22, 2009
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Author Affiliations
University of California, Davis
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