Fluorescence tomography can resolve fluorescence biodistribution in vivo with high sensitivity. We use structural information from X-ray CT as priors in the fluorescence reconstruction for improved accuracy, as shown previously. The method was tested on different phantoms and animal models and cross-validated with XCT data, histology and ex vivo fluorescence.
© OSA, IEEE Photonics Society, SPIE, COS, CIC
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.7440) Medical optics and biotechnology : X-ray imaging
R. B. Schulz, A. Ale, M. Freyer, A. Sarantopoulos, M. Zientkowska, and V. Ntziachristos, "Hybrid FMT/XCT System Validated with ex vivo Fluorescence," in Asia Communications and Photonics Conference and Exhibition, Technical Digest (CD) (Optical Society of America, 2009), paper TuCC2.
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