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Hybrid FMT/XCT system validated with ex-vivo fluorescence

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Abstract

Fluorescence tomography can resolve fluorescence biodistribution in vivo with high sensitivity. We use structural information from X-ray CT as priors in the fluorescence reconstruction for improved accuracy, as shown previously [1]. The method was tested on different phantoms and animal models and cross-validated with XCT data, histology and ex vivo fluorescence.

© 2009 OSA, IEEE Photonics Society, SPIE, COS, CIC

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