Herein a two-step Tikhonov regularization-based reconstruction algorithm in fluorescence molecular tomography (FMT) was proposed. The suboptimal and optimal parameter was obtained in two steps alternately. Experimental results suggested that such technique outperform the traditional L-curve criterion that estimating the optimal parameter when applying into the FMT reconstruction.
© OSA, IEEE Photonics Society, SPIE, COS, CIC
(110.0110) Imaging systems : Imaging systems
(110.6960) Imaging systems : Tomography
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.3010) Medical optics and biotechnology : Image reconstruction techniques
Z. Xu, Y. Jin, and J. Bai, "Determining the Regularization Parameter: A Hybrid Reconstruction Technique in Fluorescence Molecular Tomography," in Asia Communications and Photonics Conference and Exhibition, Technical Digest (CD) (Optical Society of America, 2009), paper TuG6.
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