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Endoscope-based autofluorescence imaging and point spectroscopy for improving cancer detection in the larynx

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Abstract

Autofluorescence imaging has shown high sensitivity for early diagnosis and detection of cancer in humans. However, it has a limitation diagnostic specificity due to high false positive rates. In our study, we develop an integrated fluorescence endoscopic imaging and point spectroscopy system for real-time tissue measurements. The results show that endoscope-based autofluorescene spectroscopy and imaging system has the potential for improving laryngeal cancer diagnosis and detection.

© 2009 OSA, IEEE Photonics Society, SPIE, COS, CIC

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