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Diffuse reflectance spectroscopy as an in vivo tool for characterizing changes in tissue organization during neoplastic development

I. Georgakoudi, V. Backman, M. Muller, M. Wallace, B. Jacobson, K. Badizadegan, A. Wax, M. Kalashnikov, M. Hunter, R. Dasari, J. Van Dam, and M. Feld

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Abstract

Diffuse reflectance spectra are analyzed using a light-diffusion-theory-based model, which assumes that tissue scattering can be simulated by Mie scattering with an inverse power-law particle size distribution. Diagnostic information related to tissue organization is extracted.

© 2002 Optical Society of America

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