We present noninvasive in vivo measurements of methemoglobin (MetHb) formation and reduction in rabbits using diffuse optical spectroscopy. The absolute concentrations of MetHb, Hb-R, and Hb-O2 were quantified during nitrite infusions and methylene blue treatment.
© Optical Society of America
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.1470) Medical optics and biotechnology : Blood or tissue constituent monitoring
(170.5280) Medical optics and biotechnology : Photon migration
J. Lee, A. E. Cerussi, B. J. Tromberg, N. El-Abaddi, A. Duke, and M. Brenner, "Quantitative in vivo monitoring of methemoglobinemia using noninvasive Diffuse Optical Spectroscopy," in Biomedical Topical Meeting, OSA Technical Digest (Optical Society of America, 2004), paper SH3.
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