Polystyrene microspheres were previously reported to reduce fluorophore quantum yield via collisional quenching in fluorescein-based tissue-simulating phantoms. Here, we report decreases of fluorescence intensities and lifetimes of ~10-30% that are dependent on microsphere size.
© Optical Society of America
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.6280) Medical optics and biotechnology : Spectroscopy, fluorescence and luminescence
(170.7050) Medical optics and biotechnology : Turbid media
W. Zhong, K. Vishwanath, and M. Mycek, "Characteristics of fluorescence quenching by polystyrene microspheres in tissue-simulating phantoms," in Biomedical Topical Meeting, OSA Technical Digest (Optical Society of America, 2004), paper ThF13.