A novel heterodyne dual-beam interferometer is used to perform non-contact measurements of swelling displacements in a lobster nerve bundle during the action potential. Displacements are ~1-8 nm in amplitude and ~10 ms in duration.
© Optical Society of America
(120.0120) Instrumentation, measurement, and metrology : Instrumentation, measurement, and metrology
(120.3180) Instrumentation, measurement, and metrology : Interferometry
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.3880) Medical optics and biotechnology : Medical and biological imaging
C. M. Fang-Yen, M. Chu, H. S. Seung, K. Badizadegan, R. Dasari, and M. S. Feld, "Neural interferometry: first non-contact measurements of action potential-induced nerve swelling," in Biomedical Topical Meeting, OSA Technical Digest (Optical Society of America, 2004), paper WE6.
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