Abstract
Here we present a pilot study on vascular targeting drug combretastatin A4- phosphate (CA4P) in K1735 malignant melanoma tumor models. The results show that CA4P induces a drastic decrease in blood flow and oxygen saturation. These results correlated well with contrast enhanced Ultrasound and nitroimidazole (EF5) binding.
© 2006 Optical Society of America
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