A Direct Linear Reconstruction Method for Spectrally Resolved 3D Bioluminescence Tomography

Hamid Dehghani; Robert Diplock; Brian W. Pogue; Michael S. Patterson

doi:10.1364/BIO.2006.TuG5

Biomedical Optics
Technical Digest (CD) (Optica Publishing Group, 2006),
paper TuG5
•https://doi.org/10.1364/BIO.2006.TuG5

A Direct Linear Reconstruction Method for Spectrally Resolved 3D Bioluminescence Tomography

Hamid Dehghani, Robert Diplock, Brian W. Pogue, and Michael S. Patterson

Biomedical Topical Meeting 2006

Fort Lauderdale, Florida United States
19–22 March 2006
ISBN:

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Small Animal Imaging Methods (TuG)

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H. Dehghani, R. Diplock, B. W. Pogue, and M. S. Patterson, "A Direct Linear Reconstruction Method for Spectrally Resolved 3D Bioluminescence Tomography," in Biomedical Optics, Technical Digest (CD) (Optica Publishing Group, 2006), paper TuG5.

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Abstract

Spectrally-resolved BioLuminescence optical Tomography (sBLT) is used to recover images of Luciferase activity within a 3D mouse model using multi-wavelength emission data from multiple internal bioluminescence sources. The images show that the location of sources can be reconstructed accurately using a fast, direct and linear reconstruction algorithm.

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