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Observation of apparent membrane tension in red blood cells using actively stabilized Hilbert phase microscopy

Gabriel Popescu, Takahiro Ikeda, Catherine A. Best, Keisuke Goda, Kamran Badizadegan, Ramachandra R. Dasari, and Michael S. Feld

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Abstract

Stabilized Hilbert phase microscopy delivers quantitative phase images at millisecond and nanometer scales. We quantified the thermal membrane fluctuations in red blood cells and performed the first no-contact measurement of cytoskeleton-induced cell membrane tension.

© 2006 Optical Society of America

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