Fluorescent signals from mouse-tissue-like phantoms are computed using both Monte Carlo simulation and diffusion approximation. The relative difference is less than 30% for a fluorophore placed in the middle of a 3mm separated source-detector pair.
© 2006 Optical Society of America
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.3660) Medical optics and biotechnology : Light propagation in tissues
(170.6280) Medical optics and biotechnology : Spectroscopy, fluorescence and luminescence
G. Ma, J. Delorme, P. Gallant, and D. A. Boas, "Comparison of Simplified Monte Carlo Simulation and Diffusion Approximation for Fluorescent Signal from Phantoms with Typical Mouse Optical Properties," in Biomedical Optics, Technical Digest (CD) (Optical Society of America, 2006), paper TuI16.
References are not available for this paper.