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A Simultaneous NIRS-EEG Study of Seizure in the Mouse Brain

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Abstract

We measured hemodynamic responses of seizure in the mouse brain using frequency-domain near infrared spectroscopy (NIRS) and electroencephalogram (EEG). We adapted microfabricated optical holder for consistent contact of the optical fiber to the mouse brain. Our results show that the cerebral oxygenation and hemodynamics of mice can be stably monitored with EEG in the mouse brain.

© 2008 Optical Society of America

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