Indocyanine green bolus tracking to assess cerebral perfusion may benefit from fluorescence detection. We present a novel approach to depth-discriminated retrieval of the bolus shape by empirical estimation of time-resolved intra- and extracerebral sensitivity functions.
© 2008 Optical Society of America
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.6920) Medical optics and biotechnology : Time-resolved imaging
(300.0300) Spectroscopy : Spectroscopy
(300.2530) Spectroscopy : Fluorescence, laser-induced
H. Wabnitz, A. Jelzow, R. Macdonald, H. Obrig, and J. Steinbrink, "Recovery of Indocyanine Green Boli in the Cortex of Adult Humans from Time-Resolved in vivo Fluorescence Measurements," in Biomedical Optics, OSA Technical Digest (CD) (Optical Society of America, 2008), paper BSuC4.
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