Abstract
Near-infrared (NIR) fluorescence quantum dot (QD) has great potential for studying physiological and pathophysiological processes noninvasively in several locations of the body. In this study, we firstly applied NIR QD to the mouse brain in vivo and determined the minimal detectable quantity of QD and the maximum detectable depth of QD in the mouse brain. We also monitored the clearance of QD in terms of the total intensity of fluorescence over time.
© 2008 Optical Society of America
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