A diffuse optical spectrometer was used to monitor 4T1 breast carcinoma tumors implanted in mice. Animals treated with doxorubicin showed relative increased oxygen saturation and decreased blood volume vs. controls, over a 10 day period.
© 2008 Optical Society of America
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.6510) Medical optics and biotechnology : Spectroscopy, tissue diagnostics
(170.2655) Medical optics and biotechnology : Functional monitoring and imaging
K. Vishwanath, H. Yuan, L. Moore, J. Bender, M. Dewhirst, and N. Ramanujam, "Longitudinal Monitoring of 4T1-Tumor Physiology in vivo with Doxorubicin Treatment via Diffuse Optical Spectroscopy," in Biomedical Optics, OSA Technical Digest (CD) (Optical Society of America, 2008), paper BTuC3.
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