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Conference Paper
Biomedical Optics
Miami, Florida United States
April 11-14, 2010
ISBN: 978-1-55752-887-2
Advances in Non-Linear Microscopy (BMC)

Third Harmonic Generation as a Novel Technique for Imaging Myelin in the Central Nervous System

Matthew J. Farrar, William Renninger, Joseph R. Fetcho, Frank W. Wise, and Chris B. Schaffer


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We demonstrate that third harmonic generation provides a suitable modality for imaging myelination on axons in the mouse brain and spinal cord with micrometer resolution both in vivo and ex vivo.

© 2010 OSA

OCIS Codes
(180.0180) Microscopy : Microscopy
(190.0190) Nonlinear optics : Nonlinear optics
(190.4160) Nonlinear optics : Multiharmonic generation
(180.4315) Microscopy : Nonlinear microscopy

M. J. Farrar, W. Renninger, J. R. Fetcho, F. W. Wise, and C. B. Schaffer, "Third Harmonic Generation as a Novel Technique for Imaging Myelin in the Central Nervous System," in Biomedical Optics and 3-D Imaging, OSA Technical Digest (CD) (Optical Society of America, 2010), paper BMC2.

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