Logarithmic output active illumination microscopy

Kengyeh K. Chu; Daryl Lim; Jerome Mertz

doi:10.1364/BIOMED.2010.BMD6

Biomedical Optics and 3-D Imaging
OSA Technical Digest (CD) (Optica Publishing Group, 2010),
paper BMD6
•https://doi.org/10.1364/BIOMED.2010.BMD6

Logarithmic output active illumination microscopy

Kengyeh K. Chu, Daryl Lim, and Jerome Mertz

Biomedical Optics 2010

Miami, Florida United States
11–14 April 2010
ISBN: 978-1-55752-887-2

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Novel Approaches in Microscopy (BMD)

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K. K. Chu, D. Lim, and J. Mertz, "Logarithmic output active illumination microscopy," in Biomedical Optics and 3-D Imaging, OSA Technical Digest (CD) (Optica Publishing Group, 2010), paper BMD6.

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Abstract

We present an improved technique to enhance the dynamic range of multiphoton microscopy using real time feedback to control illumination power. Our system provides simultaneous improvement in weak-signal sensitivity and immunity to strong-signal saturation.

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