We developed second-harmonic generation (SHG) active nanocrystals as cell imaging probes. Highly specific labeling of the nanocrystals on the HeLa cell membrane proteins was achieved by covalently coupling antibodies onto the nanocrystals.
© 2010 OSA
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(180.0180) Microscopy : Microscopy
(180.4315) Microscopy : Nonlinear microscopy
C. Hsieh, R. Grange, Y. Pu, and D. Psaltis, "Imaging Cells with Second-Harmonic Generation Active Nanocrystals," in Biomedical Optics and 3-D Imaging, OSA Technical Digest (CD) (Optical Society of America, 2010), paper BTuC8.
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