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Intraoperative δ-aminolevulinic Acid-Induced Protoporphyrin IX Spectroscopic Quantification Improves Clinical Margin Delineation of Intracranial Tumors

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Abstract

An intraoperative hand-held fiber-optics probe was used to estimate concentration of the fluorescent molecule protoporphyrin IX in vivo for different intracranial tumors, providing evidence that use of quantitative probe measurements improves clinical tumor margin delineation.

© 2010 Optical Society of America

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