Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group

Three-dimensional Optoacoustic Imaging System and its applications for Functional and Molecular Imaging

Not Accessible

Your library or personal account may give you access

Abstract

3D optoacoustic tomography system was developed combining advantages of pulsed optical spectroscopy and high-resolution ultrasonic detection, characterized and shown to produce high-contrast 3D maps of optical absorbance through the whole body of an animal with resolution better than 0.5 mm. Much smaller tissue structures and microvessels can be visualized in case of sufficient contrast. An ultrawide-band of ultrasonic frequencies present in optoacoustic signals contains wealth of information, which can be revealed through proper filtering and post-processing. We demonstrated that either larger anatomy, such as organs or major vessels, or the smaller structures (kidney medullas, ovarian arteries) and even microvasculature can be visualized depending on methods of signal and image processing. Figures a and b below shows exemplary images of mouse anatomy and vasculature.

© 2010 Optical Society of America

PDF Article
More Like This
3D Optoacoustic Tomography: From Molecular Targets in Mouse Models to Functional Imaging of Breast Cancer

Alexander Oraevsky
AM1P.4 CLEO: Applications and Technology (CLEO:A&T) 2014

High-resolution imaging of mouse anatomy with a multi-purpose optoacoustic tomography system

Andreas Oancea, Daniel Razansky, and Vasilis Ntziachristos
808908 European Conference on Biomedical Optics (ECBO) 2011

Select as filters


Select Topics Cancel
© Copyright 2024 | Optica Publishing Group. All Rights Reserved