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Conference Paper
Biomedical Optics
Miami, Florida United States
April 28, 2012 - May 2, 2012
ISBN: 978-1-55752-942-8
Microscopy Imaging: Novel Contrast Mechanisms (BSu4B)

Ratiometric Molecular Microscopy: Towards Real-Time Quantitative Delineation of Brain Tumor Margins

Steven Y. Leigh, Danni Wang, Ye Chen, Michael J. Mandella, Henry Haeberle, Olav Solgaard, Christopher Contag, and Jonathan T. Liu  »View Author Affiliations


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An achromatic version of a micro-mirror-scanned surgical dual-axis confocal microscope has been developed for ratiometric quantification of biomarker expression as revealed by the topical application of fluorescent contrast agents.

© 2012 OSA

OCIS Codes
(170.1790) Medical optics and biotechnology : Confocal microscopy
(170.2520) Medical optics and biotechnology : Fluorescence microscopy
(170.6900) Medical optics and biotechnology : Three-dimensional microscopy

S. Y. Leigh, D. Wang, Y. Chen, M. J. Mandella, H. Haeberle, O. Solgaard, C. Contag, and J. T. Liu, "Ratiometric Molecular Microscopy: Towards Real-Time Quantitative Delineation of Brain Tumor Margins," in Biomedical Optics and 3-D Imaging, OSA Technical Digest (Optical Society of America, 2012), paper BSu4B.5.

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