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In Vivo Measurement of Carcinogenesis-Associated Shape Alterations of the Refractive Index Correlation Function

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Abstract

We employed polarization-gating spectroscopy in the azoxymethane-treated rat model of colon carcinogenesis and found differences in the shape of the refractive index correlation function that correlated with risk of neoplasia. This marker has potential in predicting tumor development.

© 2012 Optical Society of America

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