We have adapted Tip-Enhanced Raman Spectroscopy (TERS) technology to a DNA sequencing modality simultaneously sensitive to a broad spectrum of cancer-relevant lesions. Obstacles encountered while approaching single-base resolution will be discussed.
© 2011 OSA
N. Kolodziejski, R. Gurjar, and D. Wolf, "Tip Enhanced Raman Spectroscopy (TERS) Instrumentation for Probing Linearized DNA for Cancer-Specific Lesions: Challenges and Outcomes," in Optics in the Life Sciences, OSA Technical Digest (CD) (Optical Society of America, 2011), paper JTuA16.
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