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Conference Paper
Bio-Optics: Design and Application
Monterey, California United States
April 4-6, 2011
ISBN: 978-1-55752-909-1
Joint Poster Session (JTuA)

Tip Enhanced Raman Spectroscopy (TERS) Instrumentation for Probing Linearized DNA for Cancer-Specific Lesions: Challenges and Outcomes

Noah Kolodziejski, Rajan Gurjar, and David Wolf  »View Author Affiliations


http://dx.doi.org/10.1364/BODA.2011.JTuA16


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Abstract

We have adapted Tip-Enhanced Raman Spectroscopy (TERS) technology to a DNA sequencing modality simultaneously sensitive to a broad spectrum of cancer-relevant lesions. Obstacles encountered while approaching single-base resolution will be discussed.

© 2011 OSA

OCIS Codes
(170.5660) Medical optics and biotechnology : Raman spectroscopy
(170.5810) Medical optics and biotechnology : Scanning microscopy
(180.4243) Microscopy : Near-field microscopy

Citation
N. Kolodziejski, R. Gurjar, and D. Wolf, "Tip Enhanced Raman Spectroscopy (TERS) Instrumentation for Probing Linearized DNA for Cancer-Specific Lesions: Challenges and Outcomes," in Optics in the Life Sciences, OSA Technical Digest (CD) (Optical Society of America, 2011), paper JTuA16.
http://www.opticsinfobase.org/abstract.cfm?URI=BODA-2011-JTuA16


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