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Conference Paper
Conference on Lasers and Electro-Optics
San Francisco, California United States
May 16, 2004
ISBN: 1-55752-770-9
Optical Biosensors (CThI)

Biomolecular sensor based on optical spectroscopy of single gold nanoparticles

Gunnar Raschke, Stefan Kowarik, Thomas Franzl, Carsten Sönnichsen, Thomas A. Klar, Jochen Feldmann, Alfons Nichtl, and Konrad Kürzinger

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Abstract

Light-scattering spectroscopy on single gold nanoparticles is used to detect molecular binding events. We show that our method is able to detect less than 200 molecular binding events under physiological condidtions.

© 2004 Optical Society of America

OCIS Codes
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.4580) Medical optics and biotechnology : Optical diagnostics for medicine
(290.0290) Scattering : Scattering
(290.5850) Scattering : Scattering, particles

Citation
G. Raschke, S. Kowarik, T. Franzl, C. Sönnichsen, T. A. Klar, J. Feldmann, A. Nichtl, and K. Kürzinger, "Biomolecular sensor based on optical spectroscopy of single gold nanoparticles," in Conference on Lasers and Electro-Optics/International Quantum Electronics Conference and Photonic Applications Systems Technologies, Technical Digest (CD) (Optical Society of America, 2004), paper CThI2.
http://www.opticsinfobase.org/abstract.cfm?URI=CLEO-2004-CThI2


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