The BioCD spinning-disk format enables the high-frequency narrow-bandwidth detection of antigen in a high-speed optical immunoassay. We experimentally demonstrate a detection limit approaching 100 attomoles per track and sensitivity to 100 ng/ml.
© 2004 Optical Society of America
(050.0050) Diffraction and gratings : Diffraction and gratings
(050.1940) Diffraction and gratings : Diffraction
(120.0120) Instrumentation, measurement, and metrology : Instrumentation, measurement, and metrology
(120.3180) Instrumentation, measurement, and metrology : Interferometry
M. M. Varma, H. D. Inerowicz, F. E. Regnier, and D. D. Nolte, "The BioCD: A high-sensitivity spinning-disk interferometer for antigen detection," in Conference on Lasers and Electro-Optics/International Quantum Electronics Conference and Photonic Applications Systems Technologies, Technical Digest (CD) (Optical Society of America, 2004), paper CThI6.
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