A statistical approach is presented for detecting and localizing a fluorescing tumor obscured underneath millimeters of turbid medium. The method is validated in an experimental study using a mouse tumor and folate-indocyanine dye.
© 2005 Optical Society of America
(100.0100) Image processing : Image processing
(100.3010) Image processing : Image reconstruction techniques
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.6280) Medical optics and biotechnology : Spectroscopy, fluorescence and luminescence
A. B. Milstein, C. A. Bouman, K. J. Webb, M. D. Kennedy, and P. S. Low, "A Statistical Approach for Detection and Localization of a Fluorescing Mouse Tumor in Intralipid," in Conference on Lasers and Electro-Optics/Quantum Electronics and Laser Science and Photonic Applications Systems Technologies, Technical Digest (CD) (Optical Society of America, 2005), paper CThJ2.