Raman-tweezers spectroscopy has been used for the rapid detection of dipicolinic acid (DPA) of single bacterial spores and reagentless discrimination of different species of bacterial cells with principal component analysis and cluster analysis.
© 2005 Optical Society of America
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.1530) Medical optics and biotechnology : Cell analysis
(170.5660) Medical optics and biotechnology : Raman spectroscopy
C. Xie, J. Mace, M. A. Dinno, Y. Li, W. Tang, and R. J. Newton, "Raman-Tweezers Sensing: Fast Detection and Discrimination of Bacterial Spores and Vegetative Cells," in Conference on Lasers and Electro-Optics/Quantum Electronics and Laser Science and Photonic Applications Systems Technologies, Technical Digest (CD) (Optical Society of America, 2005), paper CTuP6.