Since SHG is generated by specific macromolecules, it can potentially detect early disruptions of stromal architecture. Recent pilot data suggest that neoplastic changes in feline skin can be identified based on their SHG optical signature.
© 2007 OSA
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.1870) Medical optics and biotechnology : Dermatology
(190.0190) Nonlinear optics : Nonlinear optics
(190.1900) Nonlinear optics : Diagnostic applications of nonlinear optics
K. M. Reiser and C. Rodriguez, "Detecting the Optical Signature of Malignancy with Second Harmonic Imaging," in Conference on Lasers and Electro-Optics/Quantum Electronics and Laser Science Conference and Photonic Applications Systems Technologies, OSA Technical Digest Series (CD) (Optical Society of America, 2007), paper CTuP3.
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