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Conference Paper
Conference on Lasers and Electro-Optics
San Jose, California United States
May 4-9, 2008
ISBN: 978-1-55752-859-9
High-Throughput Biosensing (CFE)

Label-Free and High-Throughput Screening of Biomolecular Interactions

Ismail E. Ozkumur, James W. Needham, David A. Bergstein, Michael Ruane, Bennett B. Goldberg, and M Selim Unlu

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Abstract

We present a simple label-free multi-analyte detection technique that is easily scalable for high-throughput screening. We have shown a sensitivity of 20pg/mm<sup>2</sup>and a minimum detectable antibody concentration of 15ng/ml for a specific antigen.

© 2008 Optical Society of America

OCIS Codes
(120.0120) Instrumentation, measurement, and metrology : Instrumentation, measurement, and metrology
(120.3180) Instrumentation, measurement, and metrology : Interferometry
(280.0280) Remote sensing and sensors : Remote sensing and sensors
(280.4788) Remote sensing and sensors : Optical sensing and sensors

Citation
I. E. Ozkumur, J. W. Needham, D. A. Bergstein, M. Ruane, B. B. Goldberg, and M. S. Unlu, "Label-Free and High-Throughput Screening of Biomolecular Interactions," in Conference on Lasers and Electro-Optics/Quantum Electronics and Laser Science Conference and Photonic Applications Systems Technologies, OSA Technical Digest (CD) (Optical Society of America, 2008), paper CFE2.
http://www.opticsinfobase.org/abstract.cfm?URI=CLEO-2008-CFE2


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