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Conference Paper
CLEO: Science and Innovations
Baltimore, Maryland United States
May 1-6, 2011
ISBN: 978-1-55752-910-7
Optofluidic Biosensing and Biomolecular Analysis (CWL)

Highly Selective Single-Nucleotide Polymorphism Detection with Optofluidic Ring Resonator Lasers

Yuze Sun and Xudong Fan  »View Author Affiliations


http://dx.doi.org/10.1364/CLEO_SI.2011.CWL6


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Abstract

Optofluidic ring resonator microlasers in conjunction with molecular beacons are used for intracavity detection of DNA single-nucleotide polymorphism. A discrimination ratio of 100 is achieved between the target DNA and single-base-mismatched DNA.

© 2011 OSA

OCIS Codes
(140.2050) Lasers and laser optics : Dye lasers
(300.6360) Spectroscopy : Spectroscopy, laser
(280.1415) Remote sensing and sensors : Biological sensing and sensors

Citation
Y. Sun and X. Fan, "Highly Selective Single-Nucleotide Polymorphism Detection with Optofluidic Ring Resonator Lasers," in CLEO:2011 - Laser Applications to Photonic Applications, OSA Technical Digest (CD) (Optical Society of America, 2011), paper CWL6.
http://www.opticsinfobase.org/abstract.cfm?URI=CLEO_SI-2011-CWL6


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