Optofluidic ring resonator microlasers in conjunction with molecular beacons are used for intracavity detection of DNA single-nucleotide polymorphism. A discrimination ratio of 100 is achieved between the target DNA and single-base-mismatched DNA.
© 2011 OSA
Y. Sun and X. Fan, "Highly Selective Single-Nucleotide Polymorphism Detection with Optofluidic Ring Resonator Lasers," in CLEO:2011 - Laser Applications to Photonic Applications, OSA Technical Digest (CD) (Optical Society of America, 2011), paper CWL6.
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