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Conferences > DH > 2012 > JM3A > JM3A.22

In vivo quantification of tumor metabolic demand in preclinical models using optical spectroscopy

Tony Jiang, Narasimhan Rajaram, Chengbo Liu, Fangyao Hu, and Nimmi Ramanujam

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Abstract

We report the dose-dependent uptake and kinetics of 2-NBDG, a fluorescent glucose analog, in pre-clinical models using intrinsic fluorescence spectroscopy. Extracted in vivo concentrations of 2-NBDG were proportional to the injected dose in tumors.

© 2012 Optical Society of America

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