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Conference Paper
European Conference on Biomedical Optics
Munich Germany
June 12, 2005
ISBN: 0-8194-5864-3
Optical Biosensing Methods and Assays (WI)

Optical Detection of Structural Changes in Atherosclerotic Plaque

Renee M. Korol, Peter B. Canham, Helen M. Finlay, Rob R. Hammond, Mackenzie Quantz, Gary G. Ferguson, and Alexandra R. Lucas


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We have demonstrated that in vitro fluorescence spectroscopic analysis of diseased carotid arteries can identify clinically relevant compositional changes in connective tissue (collagen type I, III, IV and elastin) associated with plaque remodeling and instability.

© 2005 Optical Society of America

OCIS Codes
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.1610) Medical optics and biotechnology : Clinical applications
(300.0300) Spectroscopy : Spectroscopy
(300.2530) Spectroscopy : Fluorescence, laser-induced

R. M. Korol, P. B. Canham, H. M. Finlay, R. R. Hammond, M. Quantz, G. G. Ferguson, and A. R. Lucas, "Optical Detection of Structural Changes in Atherosclerotic Plaque," in Diagnostic Optical Spectroscopy in Biomedicine III, A. Mycek, ed., Vol. 5862 of Proc. SPIE (Optical Society of America, 2005), paper WI5.

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