Confocal reflectance microscopy may enable real-time in vivo imaging and mapping of the margins of primary cutaneous melanoma. Confocal maps of primary, pigmented and amelanotic cutaneous melanomas show excellent correlation to histology. Subclinical, subsurface tumor margins may be determined for pre-surgical planning, to guide biopsy and excision.
© 2004 Optical Society of America
M. D. Elias, M. Rajadhyaksha, K. J. Busam, A. C. Halpern, and A. Marghoob, "Confocal reflectance microscopy-guided margin-mapping of melanomas for pre-surgical planning," in Frontiers in Optics 2004/Laser Science XXII/Diffractive Optics and Micro-Optics/Optical Fabrication and Testing, OSA Technical Digest Series (Optical Society of America, 2004), paper FThF2.