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  • Frontiers in Optics 2004/Laser Science XXII/Diffractive Optics and Micro-Optics/Optical Fabrication and Testing
  • OSA Technical Digest Series (Optica Publishing Group, 2004),
  • paper FTuG43
  • https://doi.org/10.1364/FIO.2004.FTuG43

Angularly resolved light scattering probes stress- induced changes in mitochondrial morphology

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Abstract

We report the ability to probe mitochondrial morphology with angularly resolved light scattering measurements of whole cells. Early apoptotic changes in mitochondrial morphology following photodynamic therapy induced oxidative stress have been detected and modeled. Scattering measurements and models have been confirmed with electron microscopy and scattering measurements from isolated mitochondria.

© 2004 Optical Society of America

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