We utilize LEBS to evaluate uninvolved mucosa in animal and human colon carcinogenesis. We demonstrate that LEBS has the potential to diagnose the earliest, histologically undetectable, precancerous alterations and may enable accurate screening without colonoscopy.
© 2005 Optical Society of America
(030.1670) Coherence and statistical optics : Coherent optical effects
(170.4580) Medical optics and biotechnology : Optical diagnostics for medicine
(290.1350) Scattering : Backscattering
(300.6170) Spectroscopy : Spectra
Y. L. Kim, Y. Liu, V. M. Turzhitsky, R. K. Wali, H. K. Roy, and V. Backman, "Low-Coherence Enhanced Backscattering (LEBS) for Colon Cancer Screening," in Frontiers in Optics, OSA Technical Digest Series (Optical Society of America, 2005), paper FMC4.
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