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Conference Paper
Frontiers in Optics
Tucson, Arizona United States
October 16-21, 2005
ISBN: 1-55752-797-0
Small Animal Imaging II (FMI)

In Vivo Measurement of pH in Tumor and Surrounding Tissue Using Fluorescence Ratio Imaging

Brant M. Kaylor, Robert A. Gatenby, and Arthur F. Gmitro


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SNARF-1, a pH-sensitive fluorescent probe, was used to perform fluorescence ratio imaging in tumor and surrounding tissue. A pH resolution of 0.042 pH units was achieved. pH gradients extending into the peritumoral region were observed.

© 2005 Optical Society of America

OCIS Codes
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(180.2520) Microscopy : Fluorescence microscopy

B. M. Kaylor, R. A. Gatenby, and A. F. Gmitro, "In Vivo Measurement of pH in Tumor and Surrounding Tissue Using Fluorescence Ratio Imaging," in Frontiers in Optics, OSA Technical Digest Series (Optical Society of America, 2005), paper FMI1.

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