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Real-Time Bio-Agents and Pathogens Detection Using Elastic and Inelastic Optical Scattering Spectroscopy Techniques

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Abstract

The authors wish to present their work on the design and experimental result of optical sensors for the purpose of real time detection of single airborne bacterial pathogens. This effort is to address the current concerns on bio-terrorist attack and nosocomial infection in hospitals. The device is meant to serve as a portable real time early warning sensor for airborne pathogens. The design objective of the sensor is to achieve simultaneous measurements of the particle size of and the intrinsic fluorescence from each individual airborne bacterium (spore or vegetative cell). The advantage of single particle optical measurement is that the data generated by such measurement is deterministic (instead of statistical average of signals from multiple particles). The data thus generated facilitate the subsequent data processing and development of alarm decision algorithm.

© 2005 Optical Society of America

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