We demonstrate the ability to image cancerous cells in a three-dimensional tissue phantoms utilizing bright two-photon luminescence from molecularly targeted gold nanorods. Nanorod labeled cells provide three orders-of-magnitude more signal than autofluorescence from unlabeled cells.
© 2007 Optical Society of America
N. J. Durr, T. Larson, D. K. Smith, B. A. Korgel, K. Sokolov, and A. Ben-Yakar, "Two-Photon Luminescence Imaging of Cancer Cells Using Molecularly Targeted Gold Nanorods," in Frontiers in Optics 2007/Laser Science XXIII/Organic Materials and Devices for Displays and Energy Conversion, OSA Technical Digest (CD) (Optical Society of America, 2007), paper FTuO5.
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