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Conference Paper
Frontiers in Optics
San Jose, California United States
September 16, 2007
ISBN: 1-55752-846-2
Nonlinear Microscopy in Biology I (FTuO)

Two-Photon Luminescence Imaging of Cancer Cells Using Molecularly Targeted Gold Nanorods

Nicholas J. Durr, Timothy Larson, Danielle K. Smith, Brian A. Korgel, Konstantin Sokolov, and Adela Ben-Yakar

http://dx.doi.org/10.1364/FIO.2007.FTuO5


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Abstract

We demonstrate the ability to image cancerous cells in a three-dimensional tissue phantoms utilizing bright two-photon luminescence from molecularly targeted gold nanorods. Nanorod labeled cells provide three orders-of-magnitude more signal than autofluorescence from unlabeled cells.

© 2007 Optical Society of America

OCIS Codes
(180.0180) Microscopy : Microscopy
(180.5810) Microscopy : Scanning microscopy
(190.0190) Nonlinear optics : Nonlinear optics
(190.4180) Nonlinear optics : Multiphoton processes

Citation
N. J. Durr, T. Larson, D. K. Smith, B. A. Korgel, K. Sokolov, and A. Ben-Yakar, "Two-Photon Luminescence Imaging of Cancer Cells Using Molecularly Targeted Gold Nanorods," in Frontiers in Optics 2007/Laser Science XXIII/Organic Materials and Devices for Displays and Energy Conversion, OSA Technical Digest (CD) (Optical Society of America, 2007), paper FTuO5.
http://www.opticsinfobase.org/abstract.cfm?URI=FiO-2007-FTuO5


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