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Conference Paper
Frontiers in Optics
Rochester, New York United States
October 19-23, 2008
ISBN: 978-1-55752-861-2
Microscopy for Diagnostics (FWD)

Biochemical and Morphological Assessment of Normal and Pre-Cancerous Engineered Tissue Using Two-Photon Excited Autofluorescence

Jonathan M. Levitt, Martin Hunter, Margaret McLaughlin-Drubin, Karl Münger, and Irene Georgakoudi

http://dx.doi.org/10.1364/FIO.2008.FWD3


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Abstract

We present a method to non-invasively identify quantitative morphological and biochemical changes between normal and pre-cancerous engineered tissue from depth resolved autofluorescence. Morphology and metabolic activity were assessed using fractal modeling spectral deconvolution.

© 2008 The Optical Society

OCIS Codes
(100.0100) Image processing : Image processing
(100.2000) Image processing : Digital image processing
(180.0180) Microscopy : Microscopy
(180.4315) Microscopy : Nonlinear microscopy

Citation
J. M. Levitt, M. Hunter, M. McLaughlin-Drubin, K. Münger, and I. Georgakoudi, "Biochemical and Morphological Assessment of Normal and Pre-Cancerous Engineered Tissue Using Two-Photon Excited Autofluorescence," in Frontiers in Optics 2008/Laser Science XXIV/Plasmonics and Metamaterials/Optical Fabrication and Testing, OSA Technical Digest (CD) (Optical Society of America, 2008), paper FWD3.
http://www.opticsinfobase.org/abstract.cfm?URI=FiO-2008-FWD3


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